Aluminium Crimp Seals Explained

A seal with a plastic Flip Off button that must be removed to expose the injection site.

Flip Off (FOT) seals are used most commonly to package parenteral drugs where it is important that the vial contents remain sterile and secure.

The Flip Off button covers the stopper and helps to keep it clean prior to use. When removed a central section of the stopper is exposed ready for needle insertion. The aluminium skirt remains in place to secure the stopper, maintaining sterility of the vial contents.

A seal with a plastic button attached to help facilitate the activation and complete removal of the seal from the container

Flip Tear Up seals can be easily removed from the vial, allowing removal of the stopper and access to the vial contents.

Flip Tear Up seals are used for non-injectables and where needle extraction is not required. They might be used in topical, oral or ophthalmic applications.

They are available in 13mm, 20mm and 32mm sizes.

A seal combining the features of the Flip Off seal with the complete removability of the Tear Off seal

Flip Off Tear Off seals provide you with flexibility in your closure. Suitable for injectables, they also offer the opportunity to remove the seal fully to gain access to the vial contents

A seal with a bridged Tear Out tab protecting the target area that must be removed to expose the injection site

Centre Tear seals are used most commonly to seal vials containing a parenteral drug. A central section of the seal can be lifted out in order to expose a central section of the stopper beneath allowing for needle insertion.

An all-aluminium seal with Tear Out tab that allows the complete removal of the closure prior to use

Complete Tear Seals can be fully removed from the vial by hand, allowing access to the vial contents. This solution would suit products that do not require sterility or extraction by needle. Complete Tear Seals might be used to seal vials containing diagnostic solutions, topical or oral products.

Manual crimping tongs are used in cases where automated or semi-automated crimping equipment isn’t warranted, for example in research laboratories and small-scale pharmaceutical manufacturing, such as for gene therapies. They can also be used inside an isolator for small-scale aseptic fill and finish operations.

It is important to ensure you have the correct crimping tongs for the type of crimp seal you are using.

You can find out more and purchase hand crimping tongs from Adelphi company, Adelphi Manufacturing here: Hand Crimping Tongs